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More than three decades after the Clean Water Act, two iconic waterways—the great coastal estuaries of Puget Sound and the Chesapeake Bay—are in perilous condition. With polluted runoff still flowing in from industry, agriculture and massive suburban development, scientists fear contamination to the food chain and drinking water for millions of people. A growing list of endangered species also is threatened in both estuaries. POISONED WATERS examines the rising hazards to human health and the ecosystem and why it's so hard to keep our waters clean.